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Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule

Dyneins are motor proteins responsible for transport in the cytoplasm and the beating of axonemes in cilia and flagella. They bind and release microtubules via a compact microtubule-binding domain (MTBD) at the end of a coiled-coil stalk. We address how cytoplasmic and axonemal dynein MTBDs bind mic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Lacey, Samuel E, He, Shaoda, Scheres, Sjors HW, Carter, Andrew P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629372/
https://ncbi.nlm.nih.gov/pubmed/31264960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47145
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