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Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION
Macromolecular complexes that exhibit continuous forms of structural flexibility pose a challenge for many existing tools in cryo-EM single-particle analysis. We describe a new tool, called multi-body refinement, which models flexible complexes as a user-defined number of rigid bodies that move inde...
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| 發表在: | eLife |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6005684/ https://ncbi.nlm.nih.gov/pubmed/29856314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36861 |
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