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Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule
Dyneins are motor proteins responsible for transport in the cytoplasm and the beating of axonemes in cilia and flagella. They bind and release microtubules via a compact microtubule-binding domain (MTBD) at the end of a coiled-coil stalk. We address how cytoplasmic and axonemal dynein MTBDs bind mic...
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| Yayımlandı: | eLife |
|---|---|
| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
eLife Sciences Publications, Ltd
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6629372/ https://ncbi.nlm.nih.gov/pubmed/31264960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47145 |
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