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Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule

Dyneins are motor proteins responsible for transport in the cytoplasm and the beating of axonemes in cilia and flagella. They bind and release microtubules via a compact microtubule-binding domain (MTBD) at the end of a coiled-coil stalk. We address how cytoplasmic and axonemal dynein MTBDs bind mic...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Lacey, Samuel E, He, Shaoda, Scheres, Sjors HW, Carter, Andrew P
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629372/
https://ncbi.nlm.nih.gov/pubmed/31264960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47145
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