Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma

Cancer development is influenced by hereditary mutations, somatic mutations due to random errors in DNA replication, or external factors. It remains unclear how distinct cell-intrinsic and -extrinsic factors affect oncogenesis within the same tissue type. We investigated murine soft-tissue sarcomas...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Lee, Chang-Lung, Mowery, Yvonne M., Daniel, Andrea R., Zhang, Dadong, Sibley, Alexander B., Delaney, Joe R., Wisdom, Amy J., Qin, Xiaodi, Wang, Xi, Caraballo, Isibel, Gresham, Jeremy, Luo, Lixia, Van Mater, David, Owzar, Kouros, Kirsch, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629293/
https://ncbi.nlm.nih.gov/pubmed/31112524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128698
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