Whole exome sequencing of radiation-induced thymic lymphoma in mouse models identifies Notch1 activation as a driver of p53 wild-type lymphoma

Mouse models of radiation-induced thymic lymphoma are widely used to study the development of radiation-induced blood cancers and to gain insights into the biology of human T-cell lymphoblastic leukemia/lymphoma. Here we aimed to identify key oncogenic drivers for the development of radiation-induce...

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Publicado no:Cancer Res
Main Authors: Lee, Chang-Lung, Brock, Kennedy D., Hasapis, Stephanie, Zhang, Dadong, Sibley, Alexander B., Qin, Xiaodi, Gresham, Jeremy S., Caraballo, Isibel, Luo, Lixia, Daniel, Andrea R., Hilton, Matthew J., Owzar, Kouros, Kirsch, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286346/
https://ncbi.nlm.nih.gov/pubmed/34035082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-2823
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