Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy

Immunotherapy fails to cure most cancer patients. Preclinical studies indicate that radiotherapy synergizes with immunotherapy, promoting radiation-induced antitumor immunity. Most preclinical immunotherapy studies utilize transplant tumor models, which overestimate patient responses. Here, we show...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Wisdom, Amy J., Mowery, Yvonne M., Hong, Cierra S., Himes, Jonathon E., Nabet, Barzin Y., Qin, Xiaodi, Zhang, Dadong, Chen, Lan, Fradin, Hélène, Patel, Rutulkumar, Bassil, Alex M., Muise, Eric S., King, Daniel A., Xu, Eric S., Carpenter, David J., Kent, Collin L., Smythe, Kimberly S., Williams, Nerissa T., Luo, Lixia, Ma, Yan, Alizadeh, Ash A., Owzar, Kouros, Diehn, Maximilian, Bradley, Todd, Kirsch, David G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746723/
https://ncbi.nlm.nih.gov/pubmed/33335088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19917-0
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