Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma

Cancer development is influenced by hereditary mutations, somatic mutations due to random errors in DNA replication, or external factors. It remains unclear how distinct cell-intrinsic and -extrinsic factors affect oncogenesis within the same tissue type. We investigated murine soft-tissue sarcomas...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Lee, Chang-Lung, Mowery, Yvonne M., Daniel, Andrea R., Zhang, Dadong, Sibley, Alexander B., Delaney, Joe R., Wisdom, Amy J., Qin, Xiaodi, Wang, Xi, Caraballo, Isibel, Gresham, Jeremy, Luo, Lixia, Van Mater, David, Owzar, Kouros, Kirsch, David G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629293/
https://ncbi.nlm.nih.gov/pubmed/31112524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128698
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