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DL5050, a Selective Agonist for the Human Constitutive Androstane Receptor
[Image: see text] The constitutive androstane receptor (CAR) is a xenobiotic sensor governing the transcription of genes involved in drug disposition, energy homeostasis, and cell proliferation. However, currently available human CAR (hCAR) agonists are nonselective, which commonly activate hCAR alo...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | ACS Med Chem Lett |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Chemical
Society
2019
|
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6627732/ https://ncbi.nlm.nih.gov/pubmed/31312405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00079 |
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