The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection

Most patients with pancreatic ductal adenocarcinoma (PDAC) undergoing curative resection relapse within months, often with liver metastases. The hepatic microenvironment determines induction and reversal of dormancy during metastasis. Both tumor growth and metastasis depend on the Tumor necrosis fac...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Miarka, Lauritz, Hauser, Charlotte, Helm, Ole, Holdhof, Dörthe, Beckinger, Silje, Egberts, Jan-Hendrik, Gundlach, Jan-Paul, Lenk, Lennart, Rahn, Sascha, Mikulits, Wolfgang, Trauzold, Anna, Sebens, Susanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627672/
https://ncbi.nlm.nih.gov/pubmed/31146405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060745
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