c-Rel is a critical mediator of NF-κB-dependent TRAIL resistance of pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) represents one of the deadliest malignancies with an overall life expectancy of 6 months despite current therapies. NF-κB signalling has been shown to be critical for this profound cell-autonomous resistance against chemotherapeutic drugs and death receptor-in...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Geismann, C, Grohmann, F, Sebens, S, Wirths, G, Dreher, A, Häsler, R, Rosenstiel, P, Hauser, C, Egberts, J-H, Trauzold, A, Schneider, G, Sipos, B, Zeissig, S, Schreiber, S, Schäfer, H, Arlt, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237244/
https://ncbi.nlm.nih.gov/pubmed/25299780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.417
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