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Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC

BACKGROUND: The death receptors TRAIL-R1 and TRAIL-R2 are frequently overexpressed in cancer and there is an emerging evidence for their important role in malignant progression, also in the case of pancreatic ductal adenocarcinoma (PDAC). In their canonical localization at the plasma membrane, TRAIL...

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Publicado en:BMC Cancer
Autores principales: Gundlach, Jan-Paul, Hauser, Charlotte, Schlegel, Franka Maria, Böger, Christine, Röder, Christian, Röcken, Christoph, Becker, Thomas, Egberts, Jan-Hendrik, Kalthoff, Holger, Trauzold, Anna
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069838/
https://ncbi.nlm.nih.gov/pubmed/30064384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4688-8
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