Compartmentalization of TNF-related apoptosis-inducing ligand (TRAIL) death receptor functions: emerging role of nuclear TRAIL-R2

Localized in the plasma membrane, death domain-containing TNF-related apoptosis-inducing ligand (TRAIL) receptors, TRAIL-R1 and TRAIL-R2, induce apoptosis and non-apoptotic signaling when crosslinked by the ligand TRAIL or by agonistic receptor-specific antibodies. Recently, an increasing body of ev...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Bertsch, U, Röder, C, Kalthoff, H, Trauzold, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454323/
https://ncbi.nlm.nih.gov/pubmed/25165876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.351
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