PTPN3 acts as a tumor suppressor and boosts TGF‐β signaling independent of its phosphatase activity

TGF‐β controls a variety of cellular functions during development. Abnormal TGF‐β responses are commonly found in human diseases such as cancer, suggesting that TGF‐β signaling must be tightly regulated. Here, we report that protein tyrosine phosphatase non‐receptor 3 (PTPN3) profoundly potentiates...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:EMBO J
Main Authors: Yuan, Bo, Liu, Jinquan, Cao, Jin, Yu, Yi, Zhang, Hanchenxi, Wang, Fei, Zhu, Yezhang, Xiao, Mu, Liu, Sisi, Ye, Youqiong, Ma, Le, Xu, Dewei, Xu, Ningyi, Li, Yi, Zhao, Bin, Xu, Pinglong, Jin, Jianping, Xu, Jianming, Chen, Xi, Shen, Li, Lin, Xia, Feng, Xin‐Hua
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2019
נושאים:
Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627230/
https://ncbi.nlm.nih.gov/pubmed/31304624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899945
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