Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment

The temporal order of DNA replication is regulated during development and is highly correlated with gene expression, histone modifications and 3D genome architecture. We tracked changes in replication timing, gene expression, and chromatin conformation capture (Hi-C) A/B compartments over the first...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Dileep, Vishnu, Wilson, Korey A., Marchal, Claire, Lyu, Xiaowen, Zhao, Peiyao A., Li, Ben, Poulet, Axel, Bartlett, Daniel A., Rivera-Mulia, Juan Carlos, Qin, Zhaohui S., Robins, Allan J., Schulz, Thomas C., Kulik, Michael J., McCord, Rachel Patton, Dekker, Job, Dalton, Stephen, Corces, Victor G., Gilbert, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627004/
https://ncbi.nlm.nih.gov/pubmed/31231024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.05.021
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