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Condensin-Driven Remodeling of X-Chromosome Topology during Dosage Compensation
The three-dimensional organization of a genome plays a critical role in regulating gene expression, yet little is known about the machinery and mechanisms that determine higher-order chromosome structure(1,2). Here we perform genome-wide chromosome conformation capture analysis, FISH, and RNA-seq to...
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Publicado no: | Nature |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4498965/ https://ncbi.nlm.nih.gov/pubmed/26030525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14450 |
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