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Donor-derived cell-free DNA detects kidney transplant rejection during nivolumab treatment

BACKGROUND: In solid organ transplant (SOT) recipients, transplant rejection during immune checkpoint inhibitor (ICI) treatment for cancer is a clinical problem. Donor-derived cell-free DNA (dd-cfDNA) can be detected in blood and is a sensitive biomarker for diagnosis of acute rejection in SOT recip...

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Bibliografiske detaljer
Udgivet i:J Immunother Cancer
Main Authors: Hurkmans, Daan P., Verhoeven, Jeroen G. H. P., de Leur, Kitty, Boer, Karin, Joosse, Arjen, Baan, Carla C., von der Thüsen, Jan H., van Schaik, Ron H. N., Mathijssen, Ron H. J., van der Veldt, Astrid A. M., Hesselink, Dennis A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626432/
https://ncbi.nlm.nih.gov/pubmed/31300068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0653-6
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