Donor-derived cell-free DNA detects kidney transplant rejection during nivolumab treatment

BACKGROUND: In solid organ transplant (SOT) recipients, transplant rejection during immune checkpoint inhibitor (ICI) treatment for cancer is a clinical problem. Donor-derived cell-free DNA (dd-cfDNA) can be detected in blood and is a sensitive biomarker for diagnosis of acute rejection in SOT recip...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Hurkmans, Daan P., Verhoeven, Jeroen G. H. P., de Leur, Kitty, Boer, Karin, Joosse, Arjen, Baan, Carla C., von der Thüsen, Jan H., van Schaik, Ron H. N., Mathijssen, Ron H. J., van der Veldt, Astrid A. M., Hesselink, Dennis A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Case Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626432/
https://ncbi.nlm.nih.gov/pubmed/31300068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0653-6
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