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Association between single-nucleotide polymorphisms and adverse events in nivolumab-treated non-small cell lung cancer patients

BACKGROUND: Treatment with PD-1 inhibitors can be hampered by severe auto-immune-related toxicities. Our objective was to identify single-nucleotide polymorphisms (SNPs) in genes previously associated with auto-immunity, which are associated with toxicities in nivolumab-treated NSCLC patients. This...

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Τόπος έκδοσης:	Br J Cancer
Κύριοι συγγραφείς:	Bins, Sander, Basak, Edwin A., el Bouazzaoui, Samira, Koolen, Stijn L. W., Oomen – de Hoop, E., van der Leest, Cor H., van der Veldt, Astrid A. M., Sleijfer, Stefan, Debets, Reno, van Schaik, Ron H. N., Aerts, Joachim G. J. V., Mathijssen, Ron H. J.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Nature Publishing Group UK 2018
Θέματα:	Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5959881/ https://ncbi.nlm.nih.gov/pubmed/29695768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0074-1
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Association between single-nucleotide polymorphisms and adverse events in nivolumab-treated non-small cell lung cancer patients

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