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Peripheral Expression of Mutant Huntingtin is a Critical Determinant of Weight Loss and Metabolic Disturbances in Huntington’s Disease

Deteriorating weight loss in patients with Huntington’s disease (HD) is a complicated peripheral manifestation and the cause remains poorly understood. Studies suggest that body weight strongly influences the clinical progression rate of HD and thereby offers a valuable target for therapeutic interv...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lakra, Priya, Aditi, Kumari, Agrawal, Namita
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626032/
https://ncbi.nlm.nih.gov/pubmed/31300691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46470-8
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