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Acidosis and Cancer: from Mechanism to Neutralization
The extracellular pH of solid tumors is unequivocally acidic due to a combination of high rates of lactic acid production (a consequence of fermentative glycolytic metabolism) and poor perfusion. This has been documented by us and others in a wide variety of solid tumor models, primarily using Magne...
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| Publicado no: | Cancer Metastasis Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6625834/ https://ncbi.nlm.nih.gov/pubmed/30806853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-019-09787-4 |
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