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Hypoxia and acidosis: immune suppressors and therapeutic targets

Due to imbalances between vascularity and cellular growth patterns, the tumour microenvironment harbours multiple metabolic stressors including hypoxia and acidosis, which have significant influences on remodelling both tumour and peritumoral tissues. These stressors are also immunosuppressive and c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunology
Hauptverfasser: Damgaci, Sultan, Ibrahim‐Hashim, Arig, Enriquez‐Navas, Pedro M., Pilon‐Thomas, Shari, Guvenis, Albert, Gillies, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002221/
https://ncbi.nlm.nih.gov/pubmed/29485185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12917
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