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Hampering the Immune Suppressors: Therapeutic Targeting of Myeloid-Derived Suppressor Cells (MDSC) in Cancer

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells with suppressive properties that preferentially expand in cancer. MDSC mainly suppress T cell proliferation and cytotoxicity, inhibit NK cell activation, and induce the differentiation and expansion of r...

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Detalhes bibliográficos
Main Authors: Albeituni, Sabrin Husein, Ding, Chuanlin, Yan, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902636/
https://ncbi.nlm.nih.gov/pubmed/24270348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000006
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