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Yeast-derived Particulate β-Glucan Treatment Subverts the Suppression of Myeloid-derived Suppressor Cells by Inducing PMN-MDSC Apoptosis and M-MDSC Differentiation to APC in Cancer

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells that promote tumor progression. Herein, we demonstrated that activation of a C-type lectin receptor, dectin-1, in MDSC differentially modulates the function of different MDSC subsets. Yeast-derived whole...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Albeituni, Sabrin H., Ding, Chuanlin, Liu, Min, Hu, Xiaoling, Luo, Fengling, Kloecker, Goetz, Bousamra, Micahel, Zhang, Huang-ge, Yan, Jun
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761495/
https://ncbi.nlm.nih.gov/pubmed/26810222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501853
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