Human neutrophils can mimic myeloid-derived suppressor cells (PMN-MDSC) and suppress microbead or lectin-induced T cell proliferation through artefactual mechanisms

We report that human conventional CD15(+) neutrophils can be isolated in the peripheral blood mononuclear cell (PBMC) layer during Ficoll gradient separation, and that they can impair T cell proliferation in vitro without concomitant neutrophil activation and killing. This effect was observed in a t...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Negorev, Dmitri, Beier, Ulf H., Zhang, Tianyi, Quatromoni, Jon G., Bhojnagarwala, Pratik, Albelda, Steven M., Singhal, Sunil, Eruslanov, Evgeniy, Lohoff, Falk W., Levine, Matthew H., Diamond, Joshua M., Christie, Jason D., Hancock, Wayne W., Akimova, Tatiana
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816646/
https://ncbi.nlm.nih.gov/pubmed/29453429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21450-6
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