Human lung tumor FOXP3(+) Tregs upregulate four “Treg-locking” transcription factors

Experimental data indicate that FOXP3(+) Tregs can markedly curtail host antitumor immune responses, but the properties of human intratumoral Tregs are still largely unknown, in part due to significant methodologic problems. We studied the phenotypic, functional, epigenetic, and transcriptional feat...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Akimova, Tatiana, Zhang, Tianyi, Negorev, Dmitri, Singhal, Sunil, Stadanlick, Jason, Rao, Abhishek, Annunziata, Michael, Levine, Matthew H., Beier, Ulf H., Diamond, Joshua M., Christie, Jason D., Albelda, Steven M., Eruslanov, Evgeniy B., Hancock, Wayne W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621877/
https://ncbi.nlm.nih.gov/pubmed/28814673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94075
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