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Human lung tumor FOXP3(+) Tregs upregulate four “Treg-locking” transcription factors

Experimental data indicate that FOXP3(+) Tregs can markedly curtail host antitumor immune responses, but the properties of human intratumoral Tregs are still largely unknown, in part due to significant methodologic problems. We studied the phenotypic, functional, epigenetic, and transcriptional feat...

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書目詳細資料
發表在:JCI Insight
Main Authors: Akimova, Tatiana, Zhang, Tianyi, Negorev, Dmitri, Singhal, Sunil, Stadanlick, Jason, Rao, Abhishek, Annunziata, Michael, Levine, Matthew H., Beier, Ulf H., Diamond, Joshua M., Christie, Jason D., Albelda, Steven M., Eruslanov, Evgeniy B., Hancock, Wayne W.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621877/
https://ncbi.nlm.nih.gov/pubmed/28814673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94075
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