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Human lung tumor FOXP3(+) Tregs upregulate four “Treg-locking” transcription factors
Experimental data indicate that FOXP3(+) Tregs can markedly curtail host antitumor immune responses, but the properties of human intratumoral Tregs are still largely unknown, in part due to significant methodologic problems. We studied the phenotypic, functional, epigenetic, and transcriptional feat...
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| 發表在: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5621877/ https://ncbi.nlm.nih.gov/pubmed/28814673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94075 |
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