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Metabolic reprogramming of myeloid-derived suppressor cells (MDSC) in cancer
MDSC undergo metabolic reprogramming in the tumor resulting in an increased fatty acid β oxidation that supports their immunosuppressive functions. Fatty acid oxidation inhibitors, used to treat coronary disease, significantly delayed tumor growth and had a significantly increased antitumor effect w...
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| Publicado no: | Oncoimmunology |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5007951/ https://ncbi.nlm.nih.gov/pubmed/27622069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1200771 |
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