Metabolic reprogramming of myeloid-derived suppressor cells (MDSC) in cancer

MDSC undergo metabolic reprogramming in the tumor resulting in an increased fatty acid β oxidation that supports their immunosuppressive functions. Fatty acid oxidation inhibitors, used to treat coronary disease, significantly delayed tumor growth and had a significantly increased antitumor effect w...

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Detaylı Bibliyografya
Yayımlandı:Oncoimmunology
Asıl Yazarlar: Al-Khami, Amir A., Rodriguez, Paulo C., Ochoa, Augusto C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2016
Konular:
Author's View
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007951/
https://ncbi.nlm.nih.gov/pubmed/27622069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1200771
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