Llwytho...

Neutralization of tumor acidity improves anti-tumor responses to immunotherapies

Cancer immunotherapies, such as immune checkpoint blockade or adoptive T cell transfer, can lead to durable responses in the clinic, but response rates remain low due to undefined suppression mechanisms. Solid tumors are characterized by a highly acidic microenvironment that might blunt the effectiv...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Res
Prif Awduron: Pilon-Thomas, Shari, Kodumudi, Krithika, El-Kenawi, Asmaa, Russell, Shonagh, Weber, Amy, Luddy, Kim, Damaghi, Mehdi, Wojtkowiak, Jon, Mulé, James, Ibrahim-Hashim, Arig, Gillies, Robert J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829106/
https://ncbi.nlm.nih.gov/pubmed/26719539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1743
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