Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB acivation

The role of mesenchymal stem cells (MSC) in osteosarcoma (OS), the most common primary tumor of bone, has not been extensively elucidated. We have recently shown that OS is characterized by interstitial acidosis, a microenvironmental condition that is similar to a wound setting, in which mesenchymal...

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Publicado en:Int J Cancer
Autores principales: Avnet, Sofia, Di Pompo, Gemma, Chano, Tokuhiro, Errani, Costantino, Ibrahim-Hashim, Arig, Gillies, Robert J., Donati, Davide Maria, Baldini, Nicola
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272857/
https://ncbi.nlm.nih.gov/pubmed/27888521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30540
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