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Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells

The glycolytic-based metabolism of cancers promotes an acidic microenvironment that is responsible for increased aggressiveness. However, the effects of acidosis on tumour metabolism have been almost unexplored. By using capillary electrophoresis with time-of-flight mass spectrometry, we observed a...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Chano, Tokuhiro, Avnet, Sofia, Kusuzaki, Katsuyuki, Bonuccelli, Gloria, Sonveaux, Pierre, Rotili, Dante, Mai, Antonello, Baldini, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859889/
https://ncbi.nlm.nih.gov/pubmed/27186436
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