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The mechanism of inhibition by acidosis of gluconeogenesis from lactate in rat liver.

1. Gluconeogenesis from lactate or pyruvate was studied in perfused livers from starved rats at perfusate pH7.4 or under conditions simulating uncompensated metabolic acidosis (perfusate pH6.7-6.8). 2. In 'acidotic' perfusions gluconeogenesis and uptake of lactate or pyruvate were decrease...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Iles, R A, Cohen, R D, Rist, A H, Baron, P G
Format: Artigo
Langue:Inglês
Publié: 1977
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1164773/
https://ncbi.nlm.nih.gov/pubmed/18143
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