17β-Estradiol protects against interleukin-1β-induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase-3 pathway

Intervertebral disc degeneration (IVDD) is the main pathological basis of spinal degenerative diseases, and aberrant apoptosis of nucleus pulposus cells (NPCs) is the main cellular process that causes IVDD. In our previous studies, 17β-estradiol (E(2)) was demonstrated to protect rat NPCs from inter...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mol Med Rep
Hlavní autoři: Guo, Hong-Tao, Yang, Si-Dong, Zhang, Feng, Liu, Sen, Yang, Da-Long, Ma, Lei, Wang, Hui, Ding, Wen-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2019
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625415/
https://ncbi.nlm.nih.gov/pubmed/31257459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10384
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky