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17β-Estradiol protects against interleukin-1β-induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase-3 pathway
Intervertebral disc degeneration (IVDD) is the main pathological basis of spinal degenerative diseases, and aberrant apoptosis of nucleus pulposus cells (NPCs) is the main cellular process that causes IVDD. In our previous studies, 17β-estradiol (E(2)) was demonstrated to protect rat NPCs from inter...
Gespeichert in:
| Veröffentlicht in: | Mol Med Rep |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6625415/ https://ncbi.nlm.nih.gov/pubmed/31257459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10384 |
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