Combined effect of 17β-estradiol and resveratrol against apoptosis induced by interleukin-1β in rat nucleus pulposus cells via PI3K/Akt/caspase-3 pathway

Background: In previous studies, both 17β-estradiol (E2) and resveratrol (RES) were reported to protect intervertebral disc cells against aberrant apoptosis. Given that E2 has a better anti-apoptotic effect with more cancer risk and RES has an anti-apoptotic effect with less cancer risk, the combine...

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Publicado en:PeerJ
Autores principales: Yang, Si-Dong, Ma, Lei, Yang, Da-Long, Ding, Wen-Yuan
Formato: Artigo
Lenguaje:Inglês
Publicado: PeerJ Inc. 2016
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730868/
https://ncbi.nlm.nih.gov/pubmed/26824000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.1640
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