Llwytho...

Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC

The AAA+ GTPase McrB powers DNA cleavage by the endonuclease McrC. The GTPase itself is activated by McrC. The architecture of the GTPase and nuclease complex, and the mechanism of their activation remained unknown. Here, we report a 3.6 Å structure of a GTPase-active and DNA-binding deficient const...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Nirwan, Neha, Itoh, Yuzuru, Singh, Pratima, Bandyopadhyay, Sutirtha, Vinothkumar, Kutti R., Amunts, Alexey, Saikrishnan, Kayarat
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624300/
https://ncbi.nlm.nih.gov/pubmed/31296862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11084-1
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!