Epigenetic Segregation of Microbial Genomes from Complex Samples Using Restriction Endonucleases HpaII and McrB

We describe continuing work to develop restriction endonucleases as tools to enrich targeted genomes of interest from diverse populations. Two approaches were developed in parallel to segregate genomic DNA based on cytosine methylation. First, the methyl-sensitive endonuclease HpaII was used to bind...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Liu, Guohong, Weston, Christopher Q., Pham, Long K., Waltz, Shannon, Barnes, Helen, King, Paula, Sphar, Dan, Yamamoto, Robert T., Forsyth, R. Allyn
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699840/
https://ncbi.nlm.nih.gov/pubmed/26727463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146064
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