Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans

Clonal expansion of HIV infected cells plays an important role in the formation and persistence of the reservoir that allows the virus to persist, in DNA form, despite effective antiretroviral therapy. We used integration site analysis to ask if there is a similar clonal expansion of SIV infected ce...

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Publicat a:PLoS Pathog
Autors principals: Ferris, Andrea L., Wells, David W., Guo, Shuang, Del Prete, Gregory Q., Swanstrom, Adrienne E., Coffin, John M., Wu, Xiaolin, Lifson, Jeffrey D., Hughes, Stephen H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619828/
https://ncbi.nlm.nih.gov/pubmed/31291371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007869
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