Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans

Clonal expansion of HIV infected cells plays an important role in the formation and persistence of the reservoir that allows the virus to persist, in DNA form, despite effective antiretroviral therapy. We used integration site analysis to ask if there is a similar clonal expansion of SIV infected ce...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Ferris, Andrea L., Wells, David W., Guo, Shuang, Del Prete, Gregory Q., Swanstrom, Adrienne E., Coffin, John M., Wu, Xiaolin, Lifson, Jeffrey D., Hughes, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619828/
https://ncbi.nlm.nih.gov/pubmed/31291371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007869
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