Neuronal d-Serine and Glycine Release Via the Asc-1 Transporter Regulates NMDA Receptor-Dependent Synaptic Activity

d-Serine and glycine are coagonists of NMDA receptors (NMDARs), but their relative contributions for several NMDAR-dependent processes are unclear. We now report that the alanine–serine–cysteine transporter-1 (Asc-1) mediates release of both d-serine and glycine from neurons, and, in turn, this modu...

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Vydáno v:J Neurosci
Hlavní autoři: Rosenberg, Dina, Artoul, Samar, Segal, Adi C., Kolodney, Goren, Radzishevsky, Inna, Dikopoltsev, Elena, Foltyn, Veronika N., Inoue, Ran, Mori, Hisashi, Billard, Jean-Marie, Wolosker, Herman
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619521/
https://ncbi.nlm.nih.gov/pubmed/23426681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3836-12.2013
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