Feedback inactivation of D-serine synthesis by NMDA receptor-elicited translocation of serine racemase to the membrane

D-serine is a physiological coagonist of N-methyl D-aspartate receptors (NMDARs) that plays a major role in several NMDAR-dependent events. In this study we investigate mechanisms regulating D-serine production by the enzyme serine racemase (SR). We now report that NMDAR activation promotes transloc...

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Detalhes bibliográficos
Main Authors: Balan, Livia, Foltyn, Veronika N., Zehl, Martin, Dumin, Elena, Dikopoltsev, Elena, Knoh, Diana, Ohno, Yusuke, Kihara, Akio, Jensen, Ole N., Radzishevsky, Inna S., Wolosker, Herman
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678608/
https://ncbi.nlm.nih.gov/pubmed/19380732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809442106
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