The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis

Synovitis, a common clinical symptom for osteoarthritis (OA) patients, is highly related to OA pathological progression and pain manifestation. The activated synovial macrophages have been demonstrated to play an important role in synovitis, but the mechanisms about macrophage activation are still n...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Ni, Zhenhong, Kuang, Liang, Chen, Hangang, Xie, Yangli, Zhang, Bin, Ouyang, Junjie, Wu, Jiangyi, Zhou, Siru, Chen, Liang, Su, Nan, Tan, QiaoYan, Luo, Xiaoqing, Chen, Bo, Chen, Shuai, Yin, Liangjun, Huang, Haiyang, Du, Xiaolan, Chen, Lin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614358/
https://ncbi.nlm.nih.gov/pubmed/31285423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1739-2
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