Loss of Fgfr1 in chondrocytes inhibits osteoarthritis by promoting autophagic activity in temporomandibular joint

Temporomandibular joint osteoarthritis (TMJ OA) is a common degenerative disease with few effective disease-modifying treatments in the clinic. Fibroblast growth factor (FGF) signaling is implicated in articular cartilage homeostasis, but the functional roles of FGFR1 in TMJ OA remain largely unknow...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Wang, Zuqiang, Huang, Junlan, Zhou, Siru, Luo, Fengtao, Tan, Qiaoyan, Sun, Xianding, Ni, Zhenhong, Chen, Hangang, Du, Xiaolan, Xie, Yangli, Chen, Lin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995513/
https://ncbi.nlm.nih.gov/pubmed/29691281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002293
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