Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice

Osteoarthritis (OA) in the temporomandibular joint (TMJ) is a common degenerative disease in adult, which is characterized by progressive destruction of the articular cartilage. To investigate the role of FGFR3 in the homeostasis of TMJ cartilage during adult stage, we generated Fgfr3(f/f); Col2a1-C...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Siru, Xie, Yangli, Li, Wei, Huang, Junlan, Wang, Zuqiang, Tang, Junzhou, Xu, Wei, Sun, Xianding, Tan, Qiaoyan, Huang, Shuo, Luo, Fengtao, Xu, Meng, Wang, Jun, Wu, Tingting, chen, Liang, Chen, Hangang, Su, Nan, Du, Xiaolan, Shen, Yue, Chen, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819201/
https://ncbi.nlm.nih.gov/pubmed/27041063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24039
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