The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis

Synovitis, a common clinical symptom for osteoarthritis (OA) patients, is highly related to OA pathological progression and pain manifestation. The activated synovial macrophages have been demonstrated to play an important role in synovitis, but the mechanisms about macrophage activation are still n...

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Vydáno v:Cell Death Dis
Hlavní autoři: Ni, Zhenhong, Kuang, Liang, Chen, Hangang, Xie, Yangli, Zhang, Bin, Ouyang, Junjie, Wu, Jiangyi, Zhou, Siru, Chen, Liang, Su, Nan, Tan, QiaoYan, Luo, Xiaoqing, Chen, Bo, Chen, Shuai, Yin, Liangjun, Huang, Haiyang, Du, Xiaolan, Chen, Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614358/
https://ncbi.nlm.nih.gov/pubmed/31285423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1739-2
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