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The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis

Synovitis, a common clinical symptom for osteoarthritis (OA) patients, is highly related to OA pathological progression and pain manifestation. The activated synovial macrophages have been demonstrated to play an important role in synovitis, but the mechanisms about macrophage activation are still n...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Ni, Zhenhong, Kuang, Liang, Chen, Hangang, Xie, Yangli, Zhang, Bin, Ouyang, Junjie, Wu, Jiangyi, Zhou, Siru, Chen, Liang, Su, Nan, Tan, QiaoYan, Luo, Xiaoqing, Chen, Bo, Chen, Shuai, Yin, Liangjun, Huang, Haiyang, Du, Xiaolan, Chen, Lin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614358/
https://ncbi.nlm.nih.gov/pubmed/31285423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1739-2
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