How RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates

Macroautophagy/autophagy mediates the degradation of ubiquitinated aggregated proteins within lysosomes in a process known as aggrephagy. The cargo receptor SQSTM1/p62 condenses aggregated proteins into larger structures and links them to the nascent autophagosomal membrane (phagophore). How the con...

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發表在:Autophagy
Main Authors: Turco, Eleonora, Witt, Marie, Abert, Christine, Bock-Bierbaum, Tobias, Su, Ming-Yuan, Trapannone, Riccardo, Sztacho, Martin, Danieli, Alberto, Shi, Xiaoshan, Zaffagnini, Gabriele, Gamper, Annamaria, Schuschnig, Martina, Fracchiolla, Dorotea, Bernklau, Daniel, Romanov, Julia, Hartl, Markus, Hurley, James H., Daumke, Oliver, Martens, Sascha
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2019
主題:
Autophagic Punctum
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613900/
https://ncbi.nlm.nih.gov/pubmed/31066340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1615306
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