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Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy

Autophagy is a major pathway for the clearance of harmful material from the cytoplasm. During autophagy, cytoplasmic material is delivered into the lysosomal system by organelles called autophagosomes. Autophagosomes form in a de novo manner and, in the course of their formation, isolate cargo mater...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Wurzer, Bettina, Zaffagnini, Gabriele, Fracchiolla, Dorotea, Turco, Eleonora, Abert, Christine, Romanov, Julia, Martens, Sascha
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684078/
https://ncbi.nlm.nih.gov/pubmed/26413874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08941
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