p62 filaments capture and present ubiquitinated cargos for autophagy

The removal of misfolded, ubiquitinated proteins is an essential part of the protein quality control. The ubiquitin‐proteasome system (UPS) and autophagy are two interconnected pathways that mediate the degradation of such proteins. During autophagy, ubiquitinated proteins are clustered in a p62‐dep...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Zaffagnini, Gabriele, Savova, Adriana, Danieli, Alberto, Romanov, Julia, Tremel, Shirley, Ebner, Michael, Peterbauer, Thomas, Sztacho, Martin, Trapannone, Riccardo, Tarafder, Abul K, Sachse, Carsten, Martens, Sascha
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830917/
https://ncbi.nlm.nih.gov/pubmed/29343546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798308
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