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Extracellular SQSTM1 as an inflammatory mediator

Excessive inflammation may lead to irreparable injury and even death, but the key mediators and underlying mechanisms remain unclear. Our recent findings indicate that SQSTM1/p62 (sequestosome 1), a well-known macroautophagy/autophagy receptor, is a lethal inflammatory mediator of sepsis and septic...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Zou, Borong, Liu, Jiao, Klionsky, Daniel J., Tang, Daolin, Kang, Rui
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751561/
https://ncbi.nlm.nih.gov/pubmed/33111608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1843253
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